Gene Detection
首页 >投资领域>Non-invasive prenatal gene sequencing

Noninvasive prenatal genetic testing technique is a safe, accurate, rapid and simple model of fetal chromosomal disease detection technology, collecting venous blood of pregnant women, free DNA was extracted from, non euploid fetal judgment on whether women harbored chromosomes using high-throughput sequencing technology. The prenatal diagnosis technology system, to reduce neonatal birth defect rate, eugenics has significant is that the technology has both is much higher than that of prenatal screening, close to the accuracy of prenatal diagnosis, and has the advantage of avoiding the characteristics of fetal intrauterine infection and abortion in pregnant women, and in 12 weeks of pregnancy can be tested.

Product introduction:

From the beginning of the 4 week of gestation, fetal free DNA can be detected in the blood of pregnant women. With the increase of gestational age, fetal free DNA content also increased. After 12 weeks of pregnancy, pregnant women were collected by the peripheral blood (5ml) and from extract free fetal DNA, using the next generation sequencing technology combined with bioinformatics analysis means, can be accurately judged whether the fetus with chromosome disease (trisomy 21, trisomy 18, trisomy 13). The best detection time of the method is in the early and middle stage of pregnancy. It has the characteristics of non invasive sampling, no abortion risk, high sensitivity and high accuracy.

21 three body (Down syndrome)18 body (Edward's syndrome)Trisomy 13 (PA Dow syndrome)
Mongolism, is live births in the highest incidence of trisomy syndrome. Children with congenital mental retardation, growth retardation, and with multiple malformations。More than patients with congenital heart disease, appearance and multiple organs severe deformity, 40% to 1 months, 5% survived to 1 years old, 1% survived to 10 years old.Live births in the most serious trisomy of chromosome abnormality in fetus of 95% above the palace will die. Due to the existence of serious neurological diseases or complex cardiac anomalies, died a few days to a few weeks in most patients after birth.


Prenatal screening / diagnostic test cycle

intended for

1 elderly (aged 35 years), to invasive prenatal diagnosis of pregnant women;

2 Tang screen results for high risk or change the value of a single indicator, not to choose a invasive prenatal diagnosis of pregnant women;

3 during pregnancy B ultrasound fetal NT value increased or other anatomical structure abnormalities, unwilling to choose a invasive prenatal diagnosis of pregnant women;

4 is not suitable for invasive prenatal diagnosis of pregnant women, such as virus carriers, placenta, placenta low, amniotic fluid is too small, RH blood type negative, abortion, threatened abortion or precious son, etc.;

5 amniotic fluid puncture cell culture failure is not willing to accept or can no longer be invasive prenatal diagnosis of pregnant women;

Sampling and reporting period

1 non invasive prenatal detection of blood and conventional venous blood sampling method is the same, 5 mL venous blood collected for detection.

2 blood does not require fasting, do not need to check in advance, as long as the normal diet, work and rest can be.

be careful:

Non invasive genetic testing can not replace amniotic fluid puncture fetal chromosome examination.